SARS-CoV-2 uses its spike protein (S) to interact with host cells, through their ACE2 receptor protein. The viewer above shows a 3D structure of human ACE2 bound to the SARS-CoV-2 Spike protein (S). ACE2 is shown in light gray, while S is shown in light green. Atomic elements are colored individually.
Each model represents a variant of human ACE2 bound to RBD. The models were refined using the docking software HADDOCK. You can load multiple models by clicking the rows in the table below. The score in each row represents how strongly the proteins are predicted to interact, where a lower score means a stronger interaction.
Clicking on "Show Contacts" displays the chemical interactions between the atoms of the loaded models as dashes.
Keep in mind that these are simplistic models and that there is very limited information you can draw from them.